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Anthracyclines suppress pheochromocytoma cell characteristics, including metastasis, through inhibition of the hypoxia signaling pathway

Pheochromocytomas (PHEOs) and paragangliomas (PGLs) are rare, neuroendocrine tumors derived from adrenal or extra-adrenal chromaffin cells, respectively. Metastases are discovered in 3-36% of patients at the time of diagnosis. Currently, only suboptimal treatment options exist. Therefore, new therap...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pang, Ying, Yang, Chunzhang, Schovanek, Jan, Wang, Herui, Bullova, Petra, Caisova, Veronika, Gupta, Garima, Wolf, Katherine I., Semenza, Gregg L., Zhuang, Zhengping, Pacak, Karel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410225/
https://ncbi.nlm.nih.gov/pubmed/28423608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16224
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