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Synaptic ERK2 Phosphorylates and Regulates Metabotropic Glutamate Receptor 1 In Vitro and in Neurons

A synaptic pool of extracellular signal-regulated kinases (ERK) controls synaptic transmission, although little is known about its underlying signaling mechanisms. Here, we found that synaptic ERK2 directly binds to postsynaptic metabotropic glutamate receptor 1a (mGluR1a). This binding is direct an...

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Vydáno v:Mol Neurobiol
Hlavní autoři: Yang, Ju Hwan, Mao, Li-Min, Choe, Eun Sang, Wang, John Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410195/
https://ncbi.nlm.nih.gov/pubmed/27796752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-016-0225-4
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