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Synaptic ERK2 Phosphorylates and Regulates Metabotropic Glutamate Receptor 1 In Vitro and in Neurons

A synaptic pool of extracellular signal-regulated kinases (ERK) controls synaptic transmission, although little is known about its underlying signaling mechanisms. Here, we found that synaptic ERK2 directly binds to postsynaptic metabotropic glutamate receptor 1a (mGluR1a). This binding is direct an...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Yang, Ju Hwan, Mao, Li-Min, Choe, Eun Sang, Wang, John Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410195/
https://ncbi.nlm.nih.gov/pubmed/27796752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-016-0225-4
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