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Lack of riluzole efficacy in the progression of the neurodegenerative phenotype in a new conditional mouse model of striatal degeneration
BACKGROUND: Huntington’s disease (HD) is a rare familial autosomal dominant neurodegenerative disorder characterized by progressive degeneration of medium spiny neurons (MSNs) located in the striatum. Currently available treatments of HD are only limited to alleviating symptoms; therefore, high expe...
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| Опубликовано в: : | PeerJ |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
PeerJ Inc.
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410142/ https://ncbi.nlm.nih.gov/pubmed/28462043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3240 |
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