Transgenic mice lacking CREB and CREM in noradrenergic and serotonergic neurons respond differently to common antidepressants on tail suspension test

Evidence exists that chronic antidepressant therapy enhances CREB levels and activity. Nevertheless, the data are not conclusive, as previous analysis of transgenic mouse models has suggested that CREB inactivation in fact contributes to antidepressant-like behavior. The aim of this study was to eva...

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Pubblicato in:Sci Rep
Autori principali: Rafa–Zabłocka, Katarzyna, Kreiner, Grzegorz, Bagińska, Monika, Kuśmierczyk, Justyna, Parlato, Rosanna, Nalepa, Irena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647346/
https://ncbi.nlm.nih.gov/pubmed/29044198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14069-6
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