The landscape of BRAF transcript and protein variants in human cancer

BACKGROUND: The BRAF protein kinase is widely studied as a cancer driver and therapeutic target. However, the regulation of its expression is not completely understood. RESULTS: Taking advantage of the RNA-seq data of more than 4800 patients belonging to 9 different cancer types, we show that BRAF m...

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Publicat a:Mol Cancer
Autors principals: Marranci, Andrea, Jiang, Zhijie, Vitiello, Marianna, Guzzolino, Elena, Comelli, Laura, Sarti, Samanta, Lubrano, Simone, Franchin, Cinzia, Echevarría-Vargas, Ileabett, Tuccoli, Andrea, Mercatanti, Alberto, Evangelista, Monica, Sportoletti, Paolo, Cozza, Giorgio, Luzi, Ettore, Capobianco, Enrico, Villanueva, Jessie, Arrigoni, Giorgio, Signore, Giovanni, Rocchiccioli, Silvia, Pitto, Letizia, Tsinoremas, Nicholas, Poliseno, Laura
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410044/
https://ncbi.nlm.nih.gov/pubmed/28454577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0645-4
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