Idiosyncratic recognition of UUG/UUA codons by modified nucleoside 5-taurinomethyluridine, τm(5)U present at ‘wobble’ position in anticodon loop of tRNA(Leu): A molecular modeling approach

Lack of naturally occurring modified nucleoside 5-taurinomethyluridine (τm(5)U) at the ‘wobble’ 34(th) position in tRNA(Leu) causes mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS). The τm(5)U(34) specifically recognizes UUG and UUA codons. Structural conseque...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kamble, Asmita S., Fandilolu, Prayagraj M., Sambhare, Susmit B., Sonawane, Kailas D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409519/
https://ncbi.nlm.nih.gov/pubmed/28453549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176756
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados