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Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements

Partitioning of ATP generation between glycolysis and oxidative phosphorylation is central to cellular bioenergetics but cumbersome to measure. We describe here how rates of ATP generation by each pathway can be calculated from simultaneous measurements of extracellular acidification and oxygen cons...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mookerjee, Shona A., Gerencser, Akos A., Nicholls, David G., Brand, Martin D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409486/
https://ncbi.nlm.nih.gov/pubmed/28270511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.774471
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