Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements

Partitioning of ATP generation between glycolysis and oxidative phosphorylation is central to cellular bioenergetics but cumbersome to measure. We describe here how rates of ATP generation by each pathway can be calculated from simultaneous measurements of extracellular acidification and oxygen cons...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Mookerjee, Shona A., Gerencser, Akos A., Nicholls, David G., Brand, Martin D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2017
Konular:
Bioenergetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409486/
https://ncbi.nlm.nih.gov/pubmed/28270511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.774471
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