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Crystal structure of 2C helicase from enterovirus 71

Enterovirus 71 (EV71) is the major pathogen responsible for outbreaks of hand, foot, and mouth disease. EV71 nonstructural protein 2C participates in many critical events throughout the virus life cycle; however, its precise role is not fully understood. Lack of a high-resolution structure made it d...

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Bibliographic Details
Published in:Sci Adv
Main Authors: Guan, Hongxin, Tian, Juan, Qin, Bo, Wojdyla, Justyna Aleksandra, Wang, Bei, Zhao, Zhendong, Wang, Meitian, Cui, Sheng
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409451/
https://ncbi.nlm.nih.gov/pubmed/28508043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1602573
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