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Genetic analysis of the Kirsten-ras-revertant 1 gene: potentiation of its tumor suppressor activity by specific point mutations.

Kirsten-ras-revertant 1 (Krev-1) cDNA encodes a ras-related protein and exhibits an activity of inducing flat revertants at certain frequencies (2-5% of total transfectants) when introduced into a v-K-ras-transformed mouse NIH 3T3 cell line, DT. Toward understanding the mechanism of action of Krev-1...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kitayama, H, Matsuzaki, T, Ikawa, Y, Noda, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54093/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2112251/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.11.4284
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