MGMT-Methylated Alleles Are Distributed Heterogeneously Within Glioma Samples Irrespective of IDH Status and Chromosome 10q Deletion

Several molecular markers drive diagnostic classification, prognostic stratification, and/or prediction of response to therapy in patients with gliomas. Among them, IDH gene mutations are valuable markers for defining subtypes and are strongly associated with epigenetic silencing of the methylguanin...

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Pubblicato in:J Neuropathol Exp Neurol
Autori principali: Fontana, Laura, Tabano, Silvia, Bonaparte, Eleonora, Marfia, Giovanni, Pesenti, Chiara, Falcone, Rossella, Augello, Claudia, Carlessi, Nicole, Silipigni, Rosamaria, Guerneri, Silvana, Campanella, Rolando, Caroli, Manuela, Maria Sirchia, Silvia, Bosari, Silvano, Miozzo, Monica
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409217/
https://ncbi.nlm.nih.gov/pubmed/27346749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlw052
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