Altered nucleocytoplasmic proteome and transcriptome distributions in an in vitro model of amyotrophic lateral sclerosis

Aberrant nucleocytoplasmic localization of proteins has been implicated in many neurodegenerative diseases. Evidence suggests that cytoplasmic mislocalization of nuclear proteins such as transactive response DNA-binding protein 43 (TDP-43) and fused in sarcoma (FUS) may be associated with neurotoxic...

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Publicado en:PLoS One
Main Authors: Kim, Jee-Eun, Hong, Yoon Ho, Kim, Jin Young, Jeon, Gye Sun, Jung, Jung Hee, Yoon, Byung-Nam, Son, Sung-Yeon, Lee, Kwang-Woo, Kim, Jong-Il, Sung, Jung-Joon
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409181/
https://ncbi.nlm.nih.gov/pubmed/28453527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176462
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