Altered nucleocytoplasmic proteome and transcriptome distributions in an in vitro model of amyotrophic lateral sclerosis

Aberrant nucleocytoplasmic localization of proteins has been implicated in many neurodegenerative diseases. Evidence suggests that cytoplasmic mislocalization of nuclear proteins such as transactive response DNA-binding protein 43 (TDP-43) and fused in sarcoma (FUS) may be associated with neurotoxic...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Kim, Jee-Eun, Hong, Yoon Ho, Kim, Jin Young, Jeon, Gye Sun, Jung, Jung Hee, Yoon, Byung-Nam, Son, Sung-Yeon, Lee, Kwang-Woo, Kim, Jong-Il, Sung, Jung-Joon
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409181/
https://ncbi.nlm.nih.gov/pubmed/28453527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176462
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