Altered nucleocytoplasmic proteome and transcriptome distributions in an in vitro model of amyotrophic lateral sclerosis

Aberrant nucleocytoplasmic localization of proteins has been implicated in many neurodegenerative diseases. Evidence suggests that cytoplasmic mislocalization of nuclear proteins such as transactive response DNA-binding protein 43 (TDP-43) and fused in sarcoma (FUS) may be associated with neurotoxic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Jee-Eun, Hong, Yoon Ho, Kim, Jin Young, Jeon, Gye Sun, Jung, Jung Hee, Yoon, Byung-Nam, Son, Sung-Yeon, Lee, Kwang-Woo, Kim, Jong-Il, Sung, Jung-Joon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409181/
https://ncbi.nlm.nih.gov/pubmed/28453527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176462
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