Altered nucleocytoplasmic proteome and transcriptome distributions in an in vitro model of amyotrophic lateral sclerosis

Aberrant nucleocytoplasmic localization of proteins has been implicated in many neurodegenerative diseases. Evidence suggests that cytoplasmic mislocalization of nuclear proteins such as transactive response DNA-binding protein 43 (TDP-43) and fused in sarcoma (FUS) may be associated with neurotoxic...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Kim, Jee-Eun, Hong, Yoon Ho, Kim, Jin Young, Jeon, Gye Sun, Jung, Jung Hee, Yoon, Byung-Nam, Son, Sung-Yeon, Lee, Kwang-Woo, Kim, Jong-Il, Sung, Jung-Joon
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409181/
https://ncbi.nlm.nih.gov/pubmed/28453527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176462
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