Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal implant infection model

The quorum sensing (QS) circuit plays a role in the precise regulation of genes controlling virulence factors and biofilm formation in Pseudomonas aeruginosa. QS-controlled biofilm formation by Pseudomonas aeruginosa in clinical settings has remained controversial due to emerging drug resistance; th...

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Udgivet i:PLoS One
Main Authors: Luo, Jing, Dong, Biying, Wang, Ke, Cai, Shuangqi, Liu, Tangjuan, Cheng, Xiaojing, Lei, Danqing, Chen, Yanling, Li, Yanan, Kong, Jinliang, Chen, Yiqiang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409170/
https://ncbi.nlm.nih.gov/pubmed/28453568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176883
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