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Photochemical Perfluoroalkylation with Pyridine N-Oxides: Mechanistic Insights and Performance on a Kilogram Scale

The direct trifluoromethylation of (hetero)arenes is a process of high importance to the pharmaceutical industry. Many reagents exist for this purpose and have found widespread use in discovery efforts; however, the step-intensive preparation of these reagents and their corresponding cost have resul...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Chem
Asıl Yazarlar: Beatty, Joel W., Douglas, James J., Miller, Richard, McAtee, Rory C., Cole, Kevin P., Stephenson, Corey R.J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409161/
https://ncbi.nlm.nih.gov/pubmed/28462396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chempr.2016.08.002
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