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Hydrogen Sulfide Ameliorates Homocysteine-Induced Cognitive Dysfunction by Inhibition of Reactive Aldehydes Involving Upregulation of ALDH2

BACKGROUND: Homocysteine, a risk factor for Alzheimer’s disease, induces cognitive dysfunction. Reactive aldehydes play an important role in cognitive dysfunction. Aldehyde-dehydrogenase 2 detoxifies reactive aldehydes. Hydrogen sulfide, a novel neuromodulator, has neuroprotective effects and regula...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Li, Min, Zhang, Ping, Wei, Hai-jun, Li, Man-Hong, Zou, Wei, Li, Xiang, Gu, Hong-Feng, Tang, Xiao-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409037/
https://ncbi.nlm.nih.gov/pubmed/27988490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyw103
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