Hydrogen sulfide inhibits homocysteine-induced endoplasmic reticulum stress and neuronal apoptosis in rat hippocampus via upregulation of the BDNF-TrkB pathway

AIM: Homocysteine (Hcy) can elicit neuronal cell death, and hyperhomocysteinemia is a strong independent risk factor for Alzheimer's disease. The aim of this study was to examine the effects of hydrogen sulfide (H(2)S) on Hcy-induced endoplasmic reticulum (ER) stress and neuronal apoptosis in r...

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Main Authors: Wei, Hai-jun, Xu, Jin-hua, Li, Man-hong, Tang, Ji-ping, Zou, Wei, Zhang, Ping, Wang, Li, Wang, Chun-yan, Tang, Xiao-qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086382/
https://ncbi.nlm.nih.gov/pubmed/24747165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.197
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