Construction and characterization of a yeast artificial chromosome library containing seven haploid human genome equivalents.

Prior to constructing a library of yeast artificial chromosomes (YACs) containing very large human DNA fragments, we performed a series of preliminary experiments aimed at developing a suitable protocol. We found an inverse relationship between YAC insert size and transformation efficiency. Evidence...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Albertsen, H M, Abderrahim, H, Cann, H M, Dausset, J, Le Paslier, D, Cohen, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54087/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2190217/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.11.4256
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