Construction and characterization of a yeast artificial chromosome library containing seven haploid human genome equivalents.

Prior to constructing a library of yeast artificial chromosomes (YACs) containing very large human DNA fragments, we performed a series of preliminary experiments aimed at developing a suitable protocol. We found an inverse relationship between YAC insert size and transformation efficiency. Evidence...

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Bibliografiske detaljer
Main Authors: Albertsen, H M, Abderrahim, H, Cann, H M, Dausset, J, Le Paslier, D, Cohen, D
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC54087/
https://ncbi.nlm.nih.gov/pubmed/2190217
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