Depletion in LpA-I:A-II particles enhances HDL-mediated endothelial protection in familial LCAT deficiency

The aim of this study was to evaluate the vasoprotective effects of HDL isolated from carriers of LCAT deficiency, which are characterized by a selective depletion of LpA-I:A-II particles and predominance of preβ migrating HDL. HDLs were isolated from LCAT-deficient carriers and tested in vitro for...

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Vydáno v:J Lipid Res
Hlavní autoři: Gomaraschi, Monica, Ossoli, Alice, Castelnuovo, Samuela, Simonelli, Sara, Pavanello, Chiara, Balzarotti, Gloria, Arca, Marcello, Di Costanzo, Alessia, Sampietro, Tiziana, Vaudo, Gaetano, Baldassarre, Damiano, Veglia, Fabrizio, Franceschini, Guido, Calabresi, Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2017
Témata:
Patient-Oriented and Epidemiological Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408617/
https://ncbi.nlm.nih.gov/pubmed/28351888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P072371
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