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Identification of enzymes involved in oxidation of phenylbutyrate

In recent years the short-chain fatty acid, 4-phenylbutyrate (PB), has emerged as a promising drug for various clinical conditions. In fact, PB has been Food and Drug Administration-approved for urea cycle disorders since 1996. PB is more potent and less toxic than its metabolite, phenylacetate (PA)...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Palir, Neža, Ruiter, Jos P. N., Wanders, Ronald J. A., Houtkooper, Riekelt H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408614/
https://ncbi.nlm.nih.gov/pubmed/28283530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M075317
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