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Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids

Because the signaling eicosanoids, epoxyeicosatrienoic acids (EETs) and HETEs, are esterified to membrane phospholipids, we asked which long-chain acyl-CoA synthetase (ACSL) isoforms would activate these molecules and whether the apparent FA substrate preferences of each ACSL isoform might differ de...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Klett, Eric L., Chen, Shufen, Yechoor, Alekhya, Lih, Fred B., Coleman, Rosalind A.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408607/
https://ncbi.nlm.nih.gov/pubmed/28209804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M072512
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