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Mice with a deficiency in CLEC-2 are protected against deep vein thrombosis

Deep vein thrombosis (DVT) with its major complication, pulmonary embolism, is a global health problem. Mechanisms of DVT remain incompletely understood. Platelets play a role in DVT, but the impact of specific platelet receptors remains unclear. Platelet C–type lectin-like receptor 2 (CLEC-2) is kn...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Payne, Holly, Ponomaryov, Tatyana, Watson, Steve P., Brill, Alexander
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408561/
https://ncbi.nlm.nih.gov/pubmed/28104688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-09-742999
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