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Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment
Efficient hematopoietic stem cell (HSC) homing is important for hematopoietic cell transplantation (HCT), especially when HSC numbers are limited, as with the use of cord blood (CB). In a screen of small molecule compounds, we identified glucocorticoid hormone signaling as an activator of CXCR4 expr...
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| Gepubliceerd in: | Nat Med |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5408457/ https://ncbi.nlm.nih.gov/pubmed/28263313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4298 |
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