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Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment

Efficient hematopoietic stem cell (HSC) homing is important for hematopoietic cell transplantation (HCT), especially when HSC numbers are limited, as with the use of cord blood (CB). In a screen of small molecule compounds, we identified glucocorticoid hormone signaling as an activator of CXCR4 expr...

詳細記述

保存先:
書誌詳細
出版年:Nat Med
主要な著者: Guo, Bin, Huang, Xinxin, Cooper, Scott, Broxmeyer, Hal E.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408457/
https://ncbi.nlm.nih.gov/pubmed/28263313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4298
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