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Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment
Efficient hematopoietic stem cell (HSC) homing is important for hematopoietic cell transplantation (HCT), especially when HSC numbers are limited, as with the use of cord blood (CB). In a screen of small molecule compounds, we identified glucocorticoid hormone signaling as an activator of CXCR4 expr...
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| 出版年: | Nat Med |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5408457/ https://ncbi.nlm.nih.gov/pubmed/28263313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4298 |
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