Long-term self-renewing human epicardial cells generated from pluripotent stem cells under defined xeno-free conditions

The epicardium contributes both multi-lineage descendants and paracrine factors to the heart during cardiogenesis and cardiac repair, underscoring its potential for cardiac regenerative medicine. Yet little is known about the cellular and molecular mechanisms that regulate human epicardial developme...

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Bibliographic Details
Published in:Nat Biomed Eng
Main Authors: Bao, Xiaoping, Lian, Xiaojun, Hacker, Timothy A., Schmuck, Eric G., Qian, Tongcheng, Bhute, Vijesh J., Han, Tianxiao, Shi, Mengxuan, Drowley, Lauren, Plowright, Alleyn, Wang, Qing-Dong, Goumans, Marie-Jose, Palecek, Sean P.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408455/
https://ncbi.nlm.nih.gov/pubmed/28462012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-016-0003
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