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Human MicroRNA-548p Decreases Hepatic ApoB Secretion and Lipid Synthesis

OBJECTIVE: MicroRNAs (miRs) play important regulatory roles in lipid metabolism. ApoB, as the only essential scaffolding protein in the assembly of very low density lipoproteins, is a target to treat hyperlipidemia and atherosclerosis. We aimed to find out miRs that reduce apoB expression. APPROACH...

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Zhou, Liye, Hussain, M. Mahmood
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408302/
https://ncbi.nlm.nih.gov/pubmed/28336556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309247
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