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Bax Inhibitor-1 regulates hepatic lipid accumulation via ApoB secretion

In this study, we explored the effects of Bax Inhibitor-1 (BI-1) on ApoB aggregation in high-fat diet (HFD)-induced hepatic lipid accumulation. After 1 week on a HFD, triglycerides and cholesterol accumulated more in the liver and were not effectively secreted into the plasma, whereas after 8 weeks,...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Lee, Hwa Young, Lee, Geum-Hwa, Bhattarai, Kashi Raj, Park, Byung-Hyun, Koo, Seung-Hoi, Kim, Hyung-Ryong, Chae, Han Jung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906294/
https://ncbi.nlm.nih.gov/pubmed/27297735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27799
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