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Bayesian inference for intratumour heterogeneity in mutations and copy number variation
Tumor samples are heterogeneous. They consist of different subclones that are characterized by differences in DNA nucleotide sequences and copy numbers on multiple loci. Heterogeneity can be measured through the identification of the subclonal copy number and sequence at a selected set of loci. Unde...
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Publicado no: | J R Stat Soc Ser C Appl Stat |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5408274/ https://ncbi.nlm.nih.gov/pubmed/28461708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/rssc.12136 |
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