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Bayesian inference for intratumour heterogeneity in mutations and copy number variation

Tumor samples are heterogeneous. They consist of different subclones that are characterized by differences in DNA nucleotide sequences and copy numbers on multiple loci. Heterogeneity can be measured through the identification of the subclonal copy number and sequence at a selected set of loci. Unde...

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Detalhes bibliográficos
Publicado no:J R Stat Soc Ser C Appl Stat
Main Authors: Lee, Juhee, Müller, Peter, Sengupta, Subhajit, Gulukota, Kamalakar, Ji, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408274/
https://ncbi.nlm.nih.gov/pubmed/28461708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/rssc.12136
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