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Bayesian inference for intratumour heterogeneity in mutations and copy number variation

Tumor samples are heterogeneous. They consist of different subclones that are characterized by differences in DNA nucleotide sequences and copy numbers on multiple loci. Heterogeneity can be measured through the identification of the subclonal copy number and sequence at a selected set of loci. Unde...

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Foilsithe in:J R Stat Soc Ser C Appl Stat
Main Authors: Lee, Juhee, Müller, Peter, Sengupta, Subhajit, Gulukota, Kamalakar, Ji, Yuan
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408274/
https://ncbi.nlm.nih.gov/pubmed/28461708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/rssc.12136
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