Marine Cyclic Guanidine Alkaloids Monanchomycalin B and Urupocidin A Act as Inhibitors of TRPV1, TRPV2 and TRPV3, but not TRPA1 Receptors

Marine sponges contain a variety of low-molecular-weight compounds including guanidine alkaloids possessing different biological activities. Monanchomycalin B and urupocidin A were isolated from the marine sponge Monanchora pulchra. We found that they act as inhibitors of the TRPV1, TRPV2, and TRPV3...

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Veröffentlicht in:Mar Drugs
Hauptverfasser: Korolkova, Yuliya, Makarieva, Tatyana, Tabakmakher, Kseniya, Shubina, Larisa, Kudryashova, Ekaterina, Andreev, Yaroslav, Mosharova, Irina, Lee, Hyi-Seung, Lee, Yeon-Ju, Kozlov, Sergey
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408233/
https://ncbi.nlm.nih.gov/pubmed/28333079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md15040087
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