Heterogeneity of Phenotype and Function Reflects the Multistage Development of T Follicular Helper Cells

T follicular helper cells (Tfh) provide crucial signals for germinal center (GC) formation, but Tfh populations are heterogeneous. While PD1(hi) Tfh are important in the GC response, the function of the PD1(lo) Tfh-like subset is unknown. We show that these cells, like the PD1(hi) GC–Tfh, depend upo...

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Publicat a:Front Immunol
Autors principals: Trüb, Marta, Barr, Tom A., Morrison, Vicky L., Brown, Sheila, Caserta, Stefano, Rixon, Jordan, Ivens, Alasdair, Gray, David
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408024/
https://ncbi.nlm.nih.gov/pubmed/28503175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00489
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