IRAK4 Deficiency in a Patient with Recurrent Pneumococcal Infections: Case Report and Review of the Literature

Primary immunodeficiencies are genetic defects of the innate or adaptive immune system, resulting in a propensity to infections. The innate immune system is the first line of defense against pathogens and is critical to recognize microbes and start the inflammatory cascade. Sensing of microbes occur...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pediatr
Hauptverfasser: Gobin, Karina, Hintermeyer, Mary, Boisson, Bertrand, Chrabieh, Maya, Ghandil, Pegah, Puel, Anne, Picard, Capucine, Casanova, Jean-Laurent, Routes, John, Verbsky, James
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Pediatrics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5408006/
https://ncbi.nlm.nih.gov/pubmed/28503543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2017.00083
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