Characterization of the Indirubin Derivative LDD970 as a Small Molecule Aurora Kinase A Inhibitor in Human Colorectal Cancer Cells

Aurora kinase A plays an essential role in mitosis including chromosome separation and cytokinesis. Aberrant expression and activity of Aurora kinase A is associated with numerous malignancies including colorectal cancer followed by poor prognosis. The aim of this study is to determine the inhibitor...

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Bibliografische gegevens
Gepubliceerd in:Immune Netw
Hoofdauteurs: Ndolo, Karyn Muzinga, Park, Kyeong Ryang, Lee, Hyo Jeong, Yoon, Kyoung Bin, Kim, Yong-Chul, Han, Sun-Young
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Korean Association of Immunologists 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407982/
https://ncbi.nlm.nih.gov/pubmed/28458622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2017.17.2.110
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