Estrogen inhibits starvation‐induced apoptosis in osteocytes by a redox‐independent process involving association of JNK and glutathione S‐transferase P1‐1

Estrogen deficiency causes bone loss as a result of microdamage, oxidative stress, and osteocyte apoptosis. A relationship between oxidative stress‐induced apoptosis, c‐Jun N‐terminal kinase (JNK) activation, and expression of factors involved in bone remodeling has been demonstrated in osteocytes....

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Domazetovic, Vladana, Fontani, Filippo, Marcucci, Gemma, Iantomasi, Teresa, Brandi, Maria Luisa, Vincenzini, Maria Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407897/
https://ncbi.nlm.nih.gov/pubmed/28469982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12216
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