Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73 to 76

We examined whether apolipoprotein E (APOE) status interacts with vascular risk factors (VRFs) to predict the progression of white matter hyperintensities (WMHs) on brain MRI scans over a specific period of life in older age when the risk of dementia increases. At age 73 years, baseline VRFs were as...

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Dades bibliogràfiques
Publicat a:Neurobiol Aging
Autors principals: Cox, Simon R., Ritchie, Stuart J., Dickie, David Alexander, Pattie, Alison, Royle, Natalie A., Corley, Janie, Aribisala, Benjamin S., Harris, Sarah E., Valdés Hernández, Maria, Gow, Alan J., Muñoz Maniega, Susana, Starr, John M., Bastin, Mark E., Wardlaw, Joanna M., Deary, Ian J.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407886/
https://ncbi.nlm.nih.gov/pubmed/28324763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.02.014
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