Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73 to 76

We examined whether apolipoprotein E (APOE) status interacts with vascular risk factors (VRFs) to predict the progression of white matter hyperintensities (WMHs) on brain MRI scans over a specific period of life in older age when the risk of dementia increases. At age 73 years, baseline VRFs were as...

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Vydáno v:Neurobiol Aging
Hlavní autoři: Cox, Simon R., Ritchie, Stuart J., Dickie, David Alexander, Pattie, Alison, Royle, Natalie A., Corley, Janie, Aribisala, Benjamin S., Harris, Sarah E., Valdés Hernández, Maria, Gow, Alan J., Muñoz Maniega, Susana, Starr, John M., Bastin, Mark E., Wardlaw, Joanna M., Deary, Ian J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407886/
https://ncbi.nlm.nih.gov/pubmed/28324763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.02.014
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