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Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73 to 76

We examined whether apolipoprotein E (APOE) status interacts with vascular risk factors (VRFs) to predict the progression of white matter hyperintensities (WMHs) on brain MRI scans over a specific period of life in older age when the risk of dementia increases. At age 73 years, baseline VRFs were as...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Cox, Simon R., Ritchie, Stuart J., Dickie, David Alexander, Pattie, Alison, Royle, Natalie A., Corley, Janie, Aribisala, Benjamin S., Harris, Sarah E., Valdés Hernández, Maria, Gow, Alan J., Muñoz Maniega, Susana, Starr, John M., Bastin, Mark E., Wardlaw, Joanna M., Deary, Ian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407886/
https://ncbi.nlm.nih.gov/pubmed/28324763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.02.014
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