A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma

Pilocytic astrocytoma (PA) is the most common pediatric brain tumor. A recurrent feature of PA is deregulation of the mitogen activated protein kinase (MAPK) pathway most often through KIAA1549-BRAF fusion, but also by other BRAF- or RAF1-gene fusions and point mutations (e.g. BRAFV600E). These feat...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Tomić, Tajana Tešan, Olausson, Josefin, Wilzén, Annica, Sabel, Magnus, Truvé, Katarina, Sjögren, Helene, Dósa, Sándor, Tisell, Magnus, Lannering, Birgitta, Enlund, Fredrik, Martinsson, Tommy, Åman, Pierre, Abel, Frida
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407815/
https://ncbi.nlm.nih.gov/pubmed/28448514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175638
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares