MHC Class II Risk Alleles and Amino Acid Residues in Idiopathic Membranous Nephropathy

Epitopes of phospholipase A2 receptor (PLA2R), the target antigen in idiopathic membranous nephropathy (iMN), must be presented by the HLA–encoded MHC class II molecules to stimulate autoantibody production. A genome–wide association study identified risk alleles at HLA and PLA2R loci, with the top...

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Detaylı Bibliyografya
Yayımlandı:J Am Soc Nephrol
Asıl Yazarlar: Cui, Zhao, Xie, Li-jun, Chen, Fang-jin, Pei, Zhi-yong, Zhang, Li-jie, Qu, Zhen, Huang, Jing, Gu, Qiu-hua, Zhang, Yi-miao, Wang, Xin, Wang, Fang, Meng, Li-qiang, Liu, Gang, Zhou, Xu-jie, Zhu, Li, Lv, Ji-cheng, Liu, Fan, Zhang, Hong, Liao, Yun-hua, Lai, Lu-hua, Ronco, Pierre, Zhao, Ming-hui
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2017
Konular:
Clinical Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407714/
https://ncbi.nlm.nih.gov/pubmed/27852637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016020114
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