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Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms

BACKGROUND: Fatty-acid-binding proteins (FABPs) are intracellular carriers for endocannabinoids, N-acylethanolamines, and related lipids. Previous work indicates that systemically administered FABP5 inhibitors produce analgesia in models of inflammatory pain. It is currently not known whether FABP i...

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Foilsithe in:Mol Pain
Main Authors: Peng, Xiaoxue, Studholme, Keith, Kanjiya, Martha P, Luk, Jennifer, Bogdan, Diane, Elmes, Matthew W, Carbonetti, Gregory, Tong, Simon, Gary Teng, Yu-Han, Rizzo, Robert C, Li, Huilin, Deutsch, Dale G, Ojima, Iwao, Rebecchi, Mario J, Puopolo, Michelino, Kaczocha, Martin
Formáid: Artigo
Teanga:Inglês
Foilsithe: SAGE Publications 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407663/
https://ncbi.nlm.nih.gov/pubmed/28326944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806917697007
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