Measurement of In Vitro Integration Activity of HIV-1 Preintegration Complexes

HIV-1 envelope proteins engage cognate receptors on the target cell surface, which leads to viral-cell membrane fusion followed by the release of the viral capsid (CA) core into the cytoplasm. Subsequently, the viral Reverse Transcriptase (RT), as part of a namesake nucleoprotein complex termed the...

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Bibliographic Details
Published in:J Vis Exp
Main Authors: Balasubramaniam, Muthukumar, Davids, Benem, Addai, Amma B., Pandhare, Jui, Dash, Chandravanu
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2017
Subjects:
Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407617/
https://ncbi.nlm.nih.gov/pubmed/28287538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54581
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