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Beyond Mitophagy: The Diversity and Complexity of Parkin Function

Parkin is an E3 ubiquitin ligase that mediates mitochondrial autophagy, or mitophagy, in multiple cell types. While discovered in the context of Parkinson’s disease, Parkin is also an important regulator of mitophagy in the heart. In addition, while most current work is focused on the role of Parkin...

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Dades bibliogràfiques
Publicat a:Circ Res
Autors principals: Shires, Sarah E., Kitsis, Richard N., Gustafsson, Åsa B.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407365/
https://ncbi.nlm.nih.gov/pubmed/28408450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.310179
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