LPS Stimulation of Cord Blood Reveals a Newborn-Specific Neutrophil Transcriptomic Response and Cytokine Production

BACKGROUND: The neonatal innate immune system differs to microbial infection both quantitatively and qualitatively when compared to adults. Here, we provide the first genome-wide ex-vivo expression profile of umbilical cord blood (UCB) neutrophils from full-term infants prior to and in response to w...

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Gepubliceerd in:Shock
Hoofdauteurs: Mathias, Brittany, Mira, Juan C., Rehfuss, Jonathan P., Rincon, Jaimar C., Ungaro, Ricardo, Nacionales, Dina C., Lopez, Cecilia, Baker, Henry V., Moldawer, Lyle L., Larson, Shawn D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407294/
https://ncbi.nlm.nih.gov/pubmed/28410545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000800
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