Parathyroid Hormone Activates Phospholipase C (PLC)-Independent Protein Kinase C Signaling Pathway via Protein Kinase A (PKA)-Dependent Mechanism: A New Defined Signaling Route Would Induce Alternative Consideration to Previous Conceptions

BACKGROUND: Parathyroid hormone (PTH) is an effective anti-osteoporosis agent, after binding to its receptor PTHR1, several signaling pathways, including cAMP/protein kinase A (PKA) and phospholipase C (PLC)/protein kinase C (PKC), are initiated through G proteins; with the cAMP/PKA pathway as the m...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Tong, Guojun, Meng, Yue, Hao, Song, Hu, Shaoyu, He, Youhua, Yan, Wenjuan, Yang, Dehong
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2017
Assuntos:
Lab/In Vitro Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407178/
https://ncbi.nlm.nih.gov/pubmed/28424452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.903699
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