Atheroprotective vaccination with MHC-II-restricted ApoB peptides induces peritoneal IL-10-producing CD4 T cells

Although immunization with major histocompatibility complex (MHC) class II-restricted apolipoprotein B (ApoB) peptides has been shown to be atheroprotective, the mechanism is unclear. Here, we investigated CD4(+) T cell populations in immunized atherosclerotic mice. Peptides (16-mers) from mouse Apo...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Kimura, Takayuki, Tse, Kevin, McArdle, Sara, Gerhardt, Teresa, Miller, Jacqueline, Mikulski, Zbigniew, Sidney, John, Sette, Alessandro, Wolf, Dennis, Ley, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407161/
https://ncbi.nlm.nih.gov/pubmed/28087520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00798.2016
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