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Can endothelial hemoglobin-α regulate nitric oxide vasodilatory signaling?

We used mathematical modeling to investigate nitric oxide (NO)-dependent vasodilatory signaling in the arteriolar wall. Detailed continuum cellular models of calcium (Ca(2+)) dynamics and membrane electrophysiology in smooth muscle and endothelial cells (EC) were coupled with models of NO signaling...

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Foilsithe in:Am J Physiol Heart Circ Physiol
Main Authors: Parikh, Jaimit, Kapela, Adam, Tsoukias, Nikolaos M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407155/
https://ncbi.nlm.nih.gov/pubmed/28130333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00315.2016
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