Human Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus–Infected Individuals Receiving Suppressive Antiretroviral Therapy

BACKGROUND. Immune activation and inflammation remain elevated in human immunodeficiency virus (HIV)–infected individuals receiving antiretroviral therapy (ART) and may contribute to HIV persistence. METHODS. Using flow cytometry expression of CD38, HLA-DR and PD-1 were measured in blood (n = 48), l...

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Veröffentlicht in:J Infect Dis
Hauptverfasser: Khoury, Gabriela, Fromentin, Rémi, Solomon, Ajantha, Hartogensis, Wendy, Killian, Marisela, Hoh, Rebecca, Somsouk, Ma, Hunt, Peter W., Girling, Valerie, Sinclair, Elizabeth, Bacchetti, Peter, Anderson, Jenny L., Hecht, Frederick M., Deeks, Steven G., Cameron, Paul U., Chomont, Nicolas, Lewin, Sharon R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407052/
https://ncbi.nlm.nih.gov/pubmed/28453847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix039
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