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Shear stress induces Gα(q/11) activation independently of G protein-coupled receptor activation in endothelial cells

Mechanochemical signal transduction occurs when mechanical forces, such as fluid shear stress, are converted into biochemical responses within the cell. The molecular mechanisms by which endothelial cells (ECs) sense/transduce shear stress into biological signals, including the nature of the mechano...

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Détails bibliographiques
Publié dans:Am J Physiol Cell Physiol
Auteurs principaux: dela Paz, Nathaniel G., Melchior, Benoît, Frangos, John A.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407018/
https://ncbi.nlm.nih.gov/pubmed/28148497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00148.2016
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