Rapid changes in shear stress induce dissociation of a Gα(q/11)–platelet endothelial cell adhesion molecule-1 complex

It has been recently shown that endothelial platelet endothelial cell adhesion molecule-1 (PECAM-1) expression is pro-atherogenic. PECAM-1 is involved in sensing rapid changes in fluid shear stress but the mechanisms for activating signalling complexes at the endothelial cell junction have yet to be...

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Main Authors: Otte, Laura A, Bell, Kelly S, Loufrani, Laurent, Yeh, Jiunn-Chern, Melchior, Benoît, Dao, Diep N, Stevens, Hazel Y, White, Charles R, Frangos, John A
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2009
Assuntos:
Cardiovascular
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697304/
https://ncbi.nlm.nih.gov/pubmed/19332487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.172643
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