Cooperation of neurotrophin receptor TrkB and Her2 in breast cancer cells facilitates brain metastases

BACKGROUND: Patients with primary breast cancer that is positive for human epidermal growth factor receptor 2 (Her2+) have a high risk of developing metastases in the brain. Despite gains with systemic control of Her2+ disease using molecular therapies, brain metastases remain recalcitrant to therap...

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Publicat a:Breast Cancer Res
Autors principals: Choy, Cecilia, Ansari, Khairul I., Neman, Josh, Hsu, Sarah, Duenas, Matthew J., Li, Hubert, Vaidehi, Nagarajan, Jandial, Rahul
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406906/
https://ncbi.nlm.nih.gov/pubmed/28446206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0844-3
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