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Targeting MYC Dependence by Metabolic Inhibitors in Cancer
MYC is a critical growth regulatory gene that is commonly overexpressed in a wide range of cancers. Therapeutic targeting of MYC transcriptional activity has long been a goal, but it has been difficult to achieve with drugs that directly block its DNA-binding ability. Additional approaches that expl...
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| Pubblicato in: | Genes (Basel) |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5406861/ https://ncbi.nlm.nih.gov/pubmed/28362357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8040114 |
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