African American exome sequencing identifies potential risk variants at Alzheimer disease loci

OBJECTIVE: In African Americans, we sought to systematically identify coding Alzheimer disease (AD) risk variants at the previously reported AD genome-wide association study (GWAS) loci genes. METHODS: We identified coding variants within genes at the 20 published AD GWAS loci by whole-exome sequenc...

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Bibliografske podrobnosti
izdano v:Neurol Genet
Main Authors: N'Songo, Aurelie, Carrasquillo, Minerva M., Wang, Xue, Burgess, Jeremy D., Nguyen, Thuy, Asmann, Yan W., Serie, Daniel J., Younkin, Steven G., Allen, Mariet, Pedraza, Otto, Duara, Ranjan, Greig Custo, Maria T., Graff-Radford, Neill R., Ertekin-Taner, Nilüfer
Format: Artigo
Jezik:Inglês
Izdano: Wolters Kluwer 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406839/
https://ncbi.nlm.nih.gov/pubmed/28480329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000141
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